Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...

Proteins carry out most of the work in the cell, and predicting their structure, function and interactions remains one of the ...

A new LMU study shows how proteins function reliably even without a stable 3D structure—and the crucial importance not only of short sequence motifs, but also of chemical characteristics. Many ...

A nerve cell resembles a vast tree with branches that communicate with thousands of other cells. To function, it depends on a ...

Efforts to unlock the mysteries of proteins, building blocks of life, have earned three scientists the 2024 Nobel Prize in chemistry. The prize goes to David Baker “for computational protein design,” ...

Malignant melanoma is one of the most dangerous forms of cancer. Around half of melanomas and about 7% of all other cancers ...

This Brush Up is sponsored by Quanterix. Learn more about tau biomarkers and clinical applications. Tau is a flexible protein that stabilizes the internal structure of neurons and supports ...

Automated, detergent-free purification preserves native membrane protein structure while supporting more reliable target ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

Researchers at the University of Twente have developed an optical method that follows the shape changes of a single protein ...

Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap, St. Jude Children's Research Hospital scientists obtained structures of SPOP in both the ...